effect of antituberculosis regimen containing ethambutol on serum magnesium level in pulmonary tuberculosis patients

نویسندگان

m abbasi nazari

p tabarsie

m azimi

j salamzadeh

چکیده

magnesium is an essential metal that has important roles in physiological function of the body organs. ethambutol is an oral antitubercular agent with chelating effects owing to its chemical structure. the aim of present study is to determine whether ethambutol usage can alter serum magnesium concentration in patients with pulmonary tuberculosis. sixty patients with diagnosis of pulmonary tuberculosis were enrolled in the study. blood samples were obtained before treatment from patients. ten days after starting anti tuberculosis therapy, second blood samples were obtained. the amounts of serum magnesium were determined in all samples by spectrophotometric method. statistical analysis showed that serum magnesium concentrations at baseline (0.61±0.08 mmol/l) and at day 10 (0.62±0.11 mmol/l) were not different. it is possible that ethambotol does not affect magnesium concentration in tuberculosis patients, however further studies about the other cationic trace elements are recommended.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of Antituberculosis Regimen Containing Ethambutol on Serum magnesium Level in Pulmonary Tuberculosis Patients

Magnesium is an essential metal that has important roles in physiological function of the body organs. Ethambutol is an oral antitubercular agent with chelating effects owing to its chemical structure. The aim of present study is to determine whether ethambutol usage can alter serum magnesium concentration in patients with pulmonary tuberculosis. Sixty patients with diagnosis of pulmonary tuber...

متن کامل

Effect of Antituberculosis Regimen Containing Ethambutol on Serum magnesium Level in Pulmonary Tuberculosis Patients

Magnesium is an essential metal that has important roles in physiological function of the body organs. Ethambutol is an oral antitubercular agent with chelating effects owing to its chemical structure. The aim of present study is to determine whether ethambutol usage can alter serum magnesium concentration in patients with pulmonary tuberculosis. Sixty patients with diagnosis of pulmonary tuber...

متن کامل

the effect of oxytetracycline on serum calcium, phosphorus and magnesium in cattle

نتایج این مطالعه نشان می دهد که مقدار کلسیم (یونیزه و تام)، منیزیم و فسفر به طور معنی داری تغییر پیدا کرد به جزء مقدار کلسیم تام و منیزیم در روش داخل عضلانی که تغییر معنی داری نداشته است. بر اساس نتایج این مطالعه می توان نتیجه گیری کرد که اکسی تتراساکلین بر روی مقادیر سرمی کلسیم و منیزیم تأثیر می گذارد باید مقدار این کاتیون ها در بیماران، در هنگامی که اکسی تتراسایکلین استفاده می شود مورد توجه ق...

15 صفحه اول

The Impact of Treatment on Serum Level of Procalcitonin in Patients with Active Pulmonary Tuberculosis

Introduction: About one third of the world's population is infected with tuberculosis (TB) and each year, about 1.5 to 2 million people die from TB. Procalcitonin (PCT) is an inflammatory marker that its level has variable Materials and Methods: This conducted on patients with pulmonary TB. Data were collected using a check list. The serum level of PCT was measured by ELISA test at the beginnin...

متن کامل

the impact of treatment on serum level of procalcitonin in patients with active pulmonary tuberculosis

introduction: about one third of the world's population is infected with tuberculosis (tb) and each year, about 1.5 to 2 million people die from tb. procalcitonin (pct) is an inflammatory marker that its level has variable materials and methods: this conducted on patients with pulmonary tb. data were collected using a check list. the serum level of pct was measured by elisa test at the beg...

متن کامل

the effect of authentic listening materials on the listening proficiency of efl learners in the intermediate level

having conducted the experiment and analysed the data, the researcher computed the groups mean scores and variances for the test relating to the research question. as the final atep, a t-test was conodonted for the hypothesis. as noted earlier, the significance level was determined at .05 and .01 respectively. the observed t-value was higher than the critical t-value at. 5 and .01 levels. conse...

15 صفحه اول

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of pharmaceutical research

جلد ۲۰۰۹، شماره ۱، صفحات ۳۳-۳۶

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023